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Replication-Independent Endogenous DNA Double-Strand Breaks in Saccharomyces cerevisiae Model

Without exposure to any DNA-damaging agents, non-dividing eukaryotic cells carry endogenous DNA double-strand breaks (EDSBs), or Replication-Independent (RIND)-EDSBs. In human cells, RIND-EDSBs are enriched in the methylated heterochromatic areas of the genome and are repaired by an ATM-dependent no...

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Detalles Bibliográficos
Autores principales:	Thongsroy, Jirapan, Matangkasombut, Oranart, Thongnak, Araya, Rattanatanyong, Prakasit, Jirawatnotai, Siwanon, Mutirangura, Apiwat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747138/ https://www.ncbi.nlm.nih.gov/pubmed/23977341 http://dx.doi.org/10.1371/journal.pone.0072706

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