Modulation of Ocular Surface Glycocalyx Barrier Function by a Galectin-3 N-terminal Deletion Mutant and Membrane-Anchored Synthetic Glycopolymers

BACKGROUND: Interaction of transmembrane mucins with the multivalent carbohydrate-binding protein galectin-3 is critical to maintaining the integrity of the ocular surface epithelial glycocalyx. This study aimed to determine whether disruption of galectin-3 multimerization and insertion of synthetic...

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Detalles Bibliográficos
Autores principales: Mauris, Jerome, Mantelli, Flavio, Woodward, Ashley M., Cao, Ziyhi, Bertozzi, Carolyn R., Panjwani, Noorjahan, Godula, Kamil, Argüeso, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747151/
https://www.ncbi.nlm.nih.gov/pubmed/23977277
http://dx.doi.org/10.1371/journal.pone.0072304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747151/
https://www.ncbi.nlm.nih.gov/pubmed/23977277
http://dx.doi.org/10.1371/journal.pone.0072304

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