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Down Regulation of T Cell Receptor Expression in COPD Pulmonary CD8 Cells

CD8 cells may contribute towards an autoimmune process in COPD. Down regulation of T cell receptor (TCR) signalling molecules occurs in autoimmune diseases with consequent T cell dysfunction. We hypothesise that TCR signalling is abnormal in COPD pulmonary CD8 cells. Micro-array gene expression anal...

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Detalles Bibliográficos
Autores principales:	Grundy, Seamus, Plumb, Jonathan, Lea, Simon, Kaur, Manminder, Ray, David, Singh, Dave
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747211/ https://www.ncbi.nlm.nih.gov/pubmed/23977094 http://dx.doi.org/10.1371/journal.pone.0071629

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