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Loss of Let-7 MicroRNA Upregulates IL-6 in Bone Marrow-Derived Mesenchymal Stem Cells Triggering a Reactive Stromal Response to Prostate Cancer

Bone marrow-derived mesenchymal stem cells (MSCs) are able to migrate to tumors, where they promote tumorigenesis and cancer metastasis. However, the molecular phenotype of the recruited MSCs at the tumor microenvironment and the genetic programs underlying their role in cancer progression remains l...

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Detalles Bibliográficos
Autores principales: Sung, Shian-Ying, Liao, Chia-Hui, Wu, Hsun-Pai, Hsiao, Wan-Chi, Wu, I-Hui, Jinpu, Yu, Lin, Sue-Hwa, Hsieh, Chia-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747243/
https://www.ncbi.nlm.nih.gov/pubmed/23977098
http://dx.doi.org/10.1371/journal.pone.0071637

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