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A population-based analysis of clustering identifies a strong genetic contribution to lethal prostate cancer

Background: Prostate cancer is a common and often deadly cancer. Decades of study have yet to identify genes that explain much familial prostate cancer. Traditional linkage analysis of pedigrees has yielded results that are rarely validated. We hypothesize that there are rare segregating variants re...

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Detalles Bibliográficos
Autores principales: Nelson, Quentin, Agarwal, Neeraj, Stephenson, Robert, Cannon-Albright, Lisa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747326/
https://www.ncbi.nlm.nih.gov/pubmed/23970893
http://dx.doi.org/10.3389/fgene.2013.00152

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