Development of Conformation Independent Computational Models for the Early Recognition of Breast Cancer Resistance Protein Substrates

ABC efflux transporters are polyspecific members of the ABC superfamily that, acting as drug and metabolite carriers, provide a biochemical barrier against drug penetration and contribute to detoxification. Their overexpression is linked to multidrug resistance issues in a diversity of diseases. Bre...

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Detalles Bibliográficos
Autores principales: Gantner, Melisa Edith, Di Ianni, Mauricio Emiliano, Ruiz, María Esperanza, Talevi, Alan, Bruno-Blanch, Luis E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747366/
https://www.ncbi.nlm.nih.gov/pubmed/23984415
http://dx.doi.org/10.1155/2013/863592

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