Cargando…

An Attempted Substitute Study of Total Skin Electron Therapy Technique by Using Helical Photon Tomotherapy with Helical Irradiation of the Total Skin Treatment: A Phantom Result

An anthropomorphic phantom was used to investigate a treatment technique and analyze the dose distributions for helical irradiation of the total skin (HITS) by helical tomotherapy (HT). Hypothetical bolus of thicknesses of 0, 10, and 15 mm was added around the phantom body to account for the dose ho...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Chi-Ta, Shiau, An-Cheng, Tien, Hui-Ju, Yeh, Hsin-Pei, Shueng, Pei-Wei, Hsieh, Chen-Hsi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747477/
https://www.ncbi.nlm.nih.gov/pubmed/23984313
http://dx.doi.org/10.1155/2013/108794
_version_ 1782280944284073984
author Lin, Chi-Ta
Shiau, An-Cheng
Tien, Hui-Ju
Yeh, Hsin-Pei
Shueng, Pei-Wei
Hsieh, Chen-Hsi
author_facet Lin, Chi-Ta
Shiau, An-Cheng
Tien, Hui-Ju
Yeh, Hsin-Pei
Shueng, Pei-Wei
Hsieh, Chen-Hsi
author_sort Lin, Chi-Ta
collection PubMed
description An anthropomorphic phantom was used to investigate a treatment technique and analyze the dose distributions for helical irradiation of the total skin (HITS) by helical tomotherapy (HT). Hypothetical bolus of thicknesses of 0, 10, and 15 mm was added around the phantom body to account for the dose homogeneity and setup uncertainty. A central core structure was assigned as a “complete block” to force the dose tangential delivery. HITS technique with prescribed dose (D (p)) of 36 Gy in 36 fractions was generated. The radiochromic EBT2 films were used for the dose measurements. The target region with 95.0% of the D (p) received by more than 95% of the PTV was obtained. The calculated mean doses for the organs at risk (OARs) were 4.69, 3.10, 3.20, and 2.94 Gy for the lung, heart, liver, and kidneys, respectively. The measurement doses on a phantom surface for a plan with 10 mm hypothetical bolus and bolus thicknesses of 0, 1, 2, and 3 mm are 89.5%, 111.4%, 116.9%, and 117.7% of D (p), respectively. HITS can provide an accurate and uniform treatment dose in the skin with limited doses to OARs and is safe to replace a total skin electron beam regimen.
format Online
Article
Text
id pubmed-3747477
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-37474772013-08-27 An Attempted Substitute Study of Total Skin Electron Therapy Technique by Using Helical Photon Tomotherapy with Helical Irradiation of the Total Skin Treatment: A Phantom Result Lin, Chi-Ta Shiau, An-Cheng Tien, Hui-Ju Yeh, Hsin-Pei Shueng, Pei-Wei Hsieh, Chen-Hsi Biomed Res Int Research Article An anthropomorphic phantom was used to investigate a treatment technique and analyze the dose distributions for helical irradiation of the total skin (HITS) by helical tomotherapy (HT). Hypothetical bolus of thicknesses of 0, 10, and 15 mm was added around the phantom body to account for the dose homogeneity and setup uncertainty. A central core structure was assigned as a “complete block” to force the dose tangential delivery. HITS technique with prescribed dose (D (p)) of 36 Gy in 36 fractions was generated. The radiochromic EBT2 films were used for the dose measurements. The target region with 95.0% of the D (p) received by more than 95% of the PTV was obtained. The calculated mean doses for the organs at risk (OARs) were 4.69, 3.10, 3.20, and 2.94 Gy for the lung, heart, liver, and kidneys, respectively. The measurement doses on a phantom surface for a plan with 10 mm hypothetical bolus and bolus thicknesses of 0, 1, 2, and 3 mm are 89.5%, 111.4%, 116.9%, and 117.7% of D (p), respectively. HITS can provide an accurate and uniform treatment dose in the skin with limited doses to OARs and is safe to replace a total skin electron beam regimen. Hindawi Publishing Corporation 2013 2013-07-31 /pmc/articles/PMC3747477/ /pubmed/23984313 http://dx.doi.org/10.1155/2013/108794 Text en Copyright © 2013 Chi-Ta Lin et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Lin, Chi-Ta
Shiau, An-Cheng
Tien, Hui-Ju
Yeh, Hsin-Pei
Shueng, Pei-Wei
Hsieh, Chen-Hsi
An Attempted Substitute Study of Total Skin Electron Therapy Technique by Using Helical Photon Tomotherapy with Helical Irradiation of the Total Skin Treatment: A Phantom Result
title An Attempted Substitute Study of Total Skin Electron Therapy Technique by Using Helical Photon Tomotherapy with Helical Irradiation of the Total Skin Treatment: A Phantom Result
title_full An Attempted Substitute Study of Total Skin Electron Therapy Technique by Using Helical Photon Tomotherapy with Helical Irradiation of the Total Skin Treatment: A Phantom Result
title_fullStr An Attempted Substitute Study of Total Skin Electron Therapy Technique by Using Helical Photon Tomotherapy with Helical Irradiation of the Total Skin Treatment: A Phantom Result
title_full_unstemmed An Attempted Substitute Study of Total Skin Electron Therapy Technique by Using Helical Photon Tomotherapy with Helical Irradiation of the Total Skin Treatment: A Phantom Result
title_short An Attempted Substitute Study of Total Skin Electron Therapy Technique by Using Helical Photon Tomotherapy with Helical Irradiation of the Total Skin Treatment: A Phantom Result
title_sort attempted substitute study of total skin electron therapy technique by using helical photon tomotherapy with helical irradiation of the total skin treatment: a phantom result
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747477/
https://www.ncbi.nlm.nih.gov/pubmed/23984313
http://dx.doi.org/10.1155/2013/108794
work_keys_str_mv AT linchita anattemptedsubstitutestudyoftotalskinelectrontherapytechniquebyusinghelicalphotontomotherapywithhelicalirradiationofthetotalskintreatmentaphantomresult
AT shiauancheng anattemptedsubstitutestudyoftotalskinelectrontherapytechniquebyusinghelicalphotontomotherapywithhelicalirradiationofthetotalskintreatmentaphantomresult
AT tienhuiju anattemptedsubstitutestudyoftotalskinelectrontherapytechniquebyusinghelicalphotontomotherapywithhelicalirradiationofthetotalskintreatmentaphantomresult
AT yehhsinpei anattemptedsubstitutestudyoftotalskinelectrontherapytechniquebyusinghelicalphotontomotherapywithhelicalirradiationofthetotalskintreatmentaphantomresult
AT shuengpeiwei anattemptedsubstitutestudyoftotalskinelectrontherapytechniquebyusinghelicalphotontomotherapywithhelicalirradiationofthetotalskintreatmentaphantomresult
AT hsiehchenhsi anattemptedsubstitutestudyoftotalskinelectrontherapytechniquebyusinghelicalphotontomotherapywithhelicalirradiationofthetotalskintreatmentaphantomresult
AT linchita attemptedsubstitutestudyoftotalskinelectrontherapytechniquebyusinghelicalphotontomotherapywithhelicalirradiationofthetotalskintreatmentaphantomresult
AT shiauancheng attemptedsubstitutestudyoftotalskinelectrontherapytechniquebyusinghelicalphotontomotherapywithhelicalirradiationofthetotalskintreatmentaphantomresult
AT tienhuiju attemptedsubstitutestudyoftotalskinelectrontherapytechniquebyusinghelicalphotontomotherapywithhelicalirradiationofthetotalskintreatmentaphantomresult
AT yehhsinpei attemptedsubstitutestudyoftotalskinelectrontherapytechniquebyusinghelicalphotontomotherapywithhelicalirradiationofthetotalskintreatmentaphantomresult
AT shuengpeiwei attemptedsubstitutestudyoftotalskinelectrontherapytechniquebyusinghelicalphotontomotherapywithhelicalirradiationofthetotalskintreatmentaphantomresult
AT hsiehchenhsi attemptedsubstitutestudyoftotalskinelectrontherapytechniquebyusinghelicalphotontomotherapywithhelicalirradiationofthetotalskintreatmentaphantomresult