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Role of the Plasma Membrane Transporter of Organic Cations OCT1 and Its Genetic Variants in Modern Liver Pharmacology

Changes in the uptake of many drugs by the target cells may dramatically affect the pharmacological response. Thus, downregulation of SLC22A1, which encodes the organic cation transporter type 1 (OCT1), may affect the response of healthy hepatocytes and liver cancer cells to cationic drugs, such as...

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Detalles Bibliográficos
Autores principales:	Lozano, Elisa, Herraez, Elisa, Briz, Oscar, Robledo, Virginia S., Hernandez-Iglesias, Jorge, Gonzalez-Hernandez, Ana, Marin, Jose J. G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747481/ https://www.ncbi.nlm.nih.gov/pubmed/23984399 http://dx.doi.org/10.1155/2013/692071

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