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CspA from Borrelia burgdorferi Inhibits the Terminal Complement Pathway

In order to survive and persist in an immunocompetent human host, Borrelia burgdorferi controls the human immune attack and blocks the damaging effects of the activated complement system. These Gram-negative spirochetes use CspA (CRASP-1) and four additional immune evasion proteins to bind combinati...

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Detalles Bibliográficos
Autores principales: Hallström, Teresia, Siegel, Corinna, Mörgelin, Matthias, Kraiczy, Peter, Skerka, Christine, Zipfel, Peter F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747585/
https://www.ncbi.nlm.nih.gov/pubmed/23943762
http://dx.doi.org/10.1128/mBio.00481-13

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