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Immune Status and Epidemiological Characteristics of Human Immunodeficiency Virus Seroconverters in Korea, 1999–2009
OBJECTIVES: The detection of HIV seroconverters increased annually since HIV antigen/antibody testing kits have been available widely in South Korea. This study aimed to identify the epidemiological characteristics of HIV seroconverters and their immune level at HIV diagnosis. METHOD: We analyzed th...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Korea Centers for Disease Control and Prevention
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747657/ https://www.ncbi.nlm.nih.gov/pubmed/24159521 http://dx.doi.org/10.1016/j.phrp.2012.11.001 |
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author | Wang, Jin-Sook Kim, Na-young Sim, Hyo Jung Choi, Byeong-Sun Kee, Mee-Kyung |
author_facet | Wang, Jin-Sook Kim, Na-young Sim, Hyo Jung Choi, Byeong-Sun Kee, Mee-Kyung |
author_sort | Wang, Jin-Sook |
collection | PubMed |
description | OBJECTIVES: The detection of HIV seroconverters increased annually since HIV antigen/antibody testing kits have been available widely in South Korea. This study aimed to identify the epidemiological characteristics of HIV seroconverters and their immune level at HIV diagnosis. METHOD: We analyzed the epidemiological and immunological characteristics of 341 HIV seroconverters among 6,008 HIV-diagnosed individuals from 1999 and 2009. The analysis of immune level and epidemiological factors of HIV seroconverters was conducted by using chi-square test on SAS version 9.1. RESULTS: The seroconverters among newly-identified HIV cases each year increased from 0.5% in 1999 to over 5% or in 2009. The sex ratio of seroconverters was 18:1 (male:female), and 33% were in their 30s, and 28% were in their 20s. Reasons for HIV testing were involvement in voluntary test due to risky behaviors (43%), and health check-up (36%). Discovery of HIV infection occurred primarily in hospitals (84%). Among seroconverters, 55 percent had a CD4 T-cell count of more than 350/μl. CONCLUSION: Korean HIV seroconverters tended to be younger at diagnosis, diagnosed during a voluntary test, and their CD4+ T-cell counts at HIV diagnosis were higher than those of non-seroconverters aall HIV-infected individuals. This study of HIV seroconverters will be important foundational in future studies on HIV incidence, disease progress, and survival rate. |
format | Online Article Text |
id | pubmed-3747657 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Korea Centers for Disease Control and Prevention |
record_format | MEDLINE/PubMed |
spelling | pubmed-37476572013-10-24 Immune Status and Epidemiological Characteristics of Human Immunodeficiency Virus Seroconverters in Korea, 1999–2009 Wang, Jin-Sook Kim, Na-young Sim, Hyo Jung Choi, Byeong-Sun Kee, Mee-Kyung Osong Public Health Res Perspect Articles OBJECTIVES: The detection of HIV seroconverters increased annually since HIV antigen/antibody testing kits have been available widely in South Korea. This study aimed to identify the epidemiological characteristics of HIV seroconverters and their immune level at HIV diagnosis. METHOD: We analyzed the epidemiological and immunological characteristics of 341 HIV seroconverters among 6,008 HIV-diagnosed individuals from 1999 and 2009. The analysis of immune level and epidemiological factors of HIV seroconverters was conducted by using chi-square test on SAS version 9.1. RESULTS: The seroconverters among newly-identified HIV cases each year increased from 0.5% in 1999 to over 5% or in 2009. The sex ratio of seroconverters was 18:1 (male:female), and 33% were in their 30s, and 28% were in their 20s. Reasons for HIV testing were involvement in voluntary test due to risky behaviors (43%), and health check-up (36%). Discovery of HIV infection occurred primarily in hospitals (84%). Among seroconverters, 55 percent had a CD4 T-cell count of more than 350/μl. CONCLUSION: Korean HIV seroconverters tended to be younger at diagnosis, diagnosed during a voluntary test, and their CD4+ T-cell counts at HIV diagnosis were higher than those of non-seroconverters aall HIV-infected individuals. This study of HIV seroconverters will be important foundational in future studies on HIV incidence, disease progress, and survival rate. Korea Centers for Disease Control and Prevention 2012-12 /pmc/articles/PMC3747657/ /pubmed/24159521 http://dx.doi.org/10.1016/j.phrp.2012.11.001 Text en Copyright ©2012, Korea Centers for Disease Control and Prevention http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Articles Wang, Jin-Sook Kim, Na-young Sim, Hyo Jung Choi, Byeong-Sun Kee, Mee-Kyung Immune Status and Epidemiological Characteristics of Human Immunodeficiency Virus Seroconverters in Korea, 1999–2009 |
title | Immune Status and Epidemiological Characteristics of Human Immunodeficiency Virus Seroconverters in Korea, 1999–2009 |
title_full | Immune Status and Epidemiological Characteristics of Human Immunodeficiency Virus Seroconverters in Korea, 1999–2009 |
title_fullStr | Immune Status and Epidemiological Characteristics of Human Immunodeficiency Virus Seroconverters in Korea, 1999–2009 |
title_full_unstemmed | Immune Status and Epidemiological Characteristics of Human Immunodeficiency Virus Seroconverters in Korea, 1999–2009 |
title_short | Immune Status and Epidemiological Characteristics of Human Immunodeficiency Virus Seroconverters in Korea, 1999–2009 |
title_sort | immune status and epidemiological characteristics of human immunodeficiency virus seroconverters in korea, 1999–2009 |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747657/ https://www.ncbi.nlm.nih.gov/pubmed/24159521 http://dx.doi.org/10.1016/j.phrp.2012.11.001 |
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