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Variant surface antigens of malaria parasites: functional and evolutionary insights from comparative gene family classification and analysis

BACKGROUND: Plasmodium parasites, the causative agents of malaria, express many variant antigens on cell surfaces. Variant surface antigens (VSAs) are typically organized into large subtelomeric gene families that play critical roles in virulence and immune evasion. Many important aspects of VSA fun...

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Detalles Bibliográficos
Autores principales: Frech, Christian, Chen, Nansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747859/
https://www.ncbi.nlm.nih.gov/pubmed/23805789
http://dx.doi.org/10.1186/1471-2164-14-427