In Vivo Delivery of Adenoviral Vector Containing Interleukin-17 Receptor A Reduces Cardiac Remodeling and Improves Myocardial Function in Viral Myocarditis Leading to Dilated Cardiomyopathy

Th17 cells have been implicated in the pathogenesis of myocarditis. Interleukin (IL)-17A produced by Th17 cells is dispensable for viral myocarditis but essential for the progression to dilated cardiomyopathy (DCM). This study investigated whether the adenoviral transfer of the IL-17 receptor A redu...

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Detalles Bibliográficos
Autores principales: Xie, Yuquan, Li, Minghui, Wang, Xinggang, Zhang, Xian, Peng, Tianqing, Yang, Yingzhen, Zou, Yunzeng, Ge, Junbo, Chen, Haozhu, Chen, Ruizhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748008/
https://www.ncbi.nlm.nih.gov/pubmed/23977238
http://dx.doi.org/10.1371/journal.pone.0072158

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