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Involvement of Endoplasmic Reticulum Stress in Albuminuria Induced Inflammasome Activation in Renal Proximal Tubular Cells

Albuminuria contributes to the progression of tubulointerstitial fibrosis. Although it has been demonstrated that ongoing albuminuria leads to tubular injury manifested by the overexpression of numerous proinflammatory cytokines, the mechanism remains largely unknown. In this study, we found that th...

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Detalles Bibliográficos
Autores principales: Fang, Li, Xie, Da, Wu, Xian, Cao, Hongdi, Su, Weifang, Yang, Junwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748031/
https://www.ncbi.nlm.nih.gov/pubmed/23977286
http://dx.doi.org/10.1371/journal.pone.0072344