Cargando…
Elimination of Von Hippel-Lindau Function Perturbs Pancreas Endocrine Homeostasis in Mice
Mutations in the human homolog of the Vhlh gene [encoding the von-Hippel Lindau (VHL) protein] lead to tumor development. In mice, depletion of Vhlh in pancreatic ß-cells causes perturbed glucose homeostasis, but the role of this gene in other pancreatic cells is poorly understood. To investigate th...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748057/ https://www.ncbi.nlm.nih.gov/pubmed/23977255 http://dx.doi.org/10.1371/journal.pone.0072213 |