Cortical region-specific engraftment of embryonic stem cell-derived neural progenitor cells restores axonal sprouting to a subcortical target and achieves motor functional recovery in a mouse model of neonatal hypoxic-ischemic brain injury

Hypoxic-ischemic encephalopathy (HIE) at birth could cause cerebral palsy (CP), mental retardation, and epilepsy, which last throughout the individual's lifetime. However, few restorative treatments for ischemic tissue are currently available. Cell replacement therapy offers the potential to re...

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Detalles Bibliográficos
Autores principales: Shinoyama, Mizuya, Ideguchi, Makoto, Kida, Hiroyuki, Kajiwara, Koji, Kagawa, Yoshiteru, Maeda, Yoshihiko, Nomura, Sadahiro, Suzuki, Michiyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748369/
https://www.ncbi.nlm.nih.gov/pubmed/23970853
http://dx.doi.org/10.3389/fncel.2013.00128

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