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Space Constrained Homology Modelling: The Paradigm of the RNA-Dependent RNA Polymerase of Dengue (Type II) Virus

Protein structure is more conserved than sequence in nature. In this direction we developed a novel methodology that significantly improves conventional homology modelling when sequence identity is low, by taking into consideration 3D structural features of the template, such as size and shape. Here...

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Detalles Bibliográficos
Autores principales:	Vlachakis, Dimitrios, Kontopoulos, Dimitrios Georgios, Kossida, Sophia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748430/ https://www.ncbi.nlm.nih.gov/pubmed/23986788 http://dx.doi.org/10.1155/2013/108910

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