APP interacts with LRP4 and agrin to coordinate the development of the neuromuscular junction in mice

ApoE, ApoE receptors and APP cooperate in the pathogenesis of Alzheimer’s disease. Intriguingly, the ApoE receptor LRP4 and APP are also required for normal formation and function of the neuromuscular junction (NMJ). In this study, we show that APP interacts with LRP4, an obligate co-receptor for mu...

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Detalles Bibliográficos
Autores principales: Choi, Hong Y, Liu, Yun, Tennert, Christian, Sugiura, Yoshie, Karakatsani, Andromachi, Kröger, Stephan, Johnson, Eric B, Hammer, Robert E, Lin, Weichun, Herz, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Developmental Biology and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748711/
https://www.ncbi.nlm.nih.gov/pubmed/23986861
http://dx.doi.org/10.7554/eLife.00220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748711/
https://www.ncbi.nlm.nih.gov/pubmed/23986861
http://dx.doi.org/10.7554/eLife.00220

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