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Preparation and characterization of monomethoxy poly(ethylene glycol)-poly(ε-caprolactone) micelles for the solubilization and in vivo delivery of luteolin
Luteolin (Lu) is one of the flavonoids with anticancer activity, but its poor water solubility limits its use clinically. In this work, we used monomethoxy poly(ethylene glycol)-poly(e-caprolactone) (MPEG-PCL) micelles to encapsulate Lu by a self-assembly method, creating a water-soluble Lu/MPEG-PCL...
Autores principales: | Qiu, Jin-Feng, Gao, Xiang, Wang, Bi-Lan, Wei, Xia-Wei, Gou, Ma-Ling, Men, Ke, Liu, Xing-Yu, Guo, Gang, Qian, Zhi-Yong, Huang, Mei-Juan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748903/ https://www.ncbi.nlm.nih.gov/pubmed/23990719 http://dx.doi.org/10.2147/IJN.S45062 |
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