Glyphosate and AMPA inhibit cancer cell growth through inhibiting intracellular glycine synthesis

Glycine is a nonessential amino acid that is reversibly converted from serine intracellularly by serine hydroxymethyltransferase. Glyphosate and its degradation product, aminomethylphosphonic acid (AMPA), are analogs to glycine, thus they may inhibit serine hydroxymethyltransferase to decrease intra...

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Detalles Bibliográficos
Autores principales: Li, Qingli, Lambrechts, Mark J, Zhang, Qiuyang, Liu, Sen, Ge, Dongxia, Yin, Rutie, Xi, Mingrong, You, Zongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749059/
https://www.ncbi.nlm.nih.gov/pubmed/23983455
http://dx.doi.org/10.2147/DDDT.S49197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749059/
https://www.ncbi.nlm.nih.gov/pubmed/23983455
http://dx.doi.org/10.2147/DDDT.S49197

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