Development and Validation of a Clinical Trial Patient Stratification Assay That Interrogates 27 Mutation Sites in MAPK Pathway Genes

Somatic mutations identified on genes related to the cancer-developing signaling pathways have drawn attention in the field of personalized medicine in recent years. Treatments developed to target a specific signaling pathway may not be effective when tumor activating mutations occur downstream of t...

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Detalles Bibliográficos
Autores principales: Chang, Ken C. N., Galuska, Stefan, Weiner, Russell, Marton, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749116/
https://www.ncbi.nlm.nih.gov/pubmed/23991070
http://dx.doi.org/10.1371/journal.pone.0072239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749116/
https://www.ncbi.nlm.nih.gov/pubmed/23991070
http://dx.doi.org/10.1371/journal.pone.0072239

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