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New Binding Site Conformations of the Dengue Virus NS3 Protease Accessed by Molecular Dynamics Simulation

Dengue fever is caused by four distinct serotypes of the dengue virus (DENV1-4), and is estimated to affect over 500 million people every year. Presently, there are no vaccines or antiviral treatments for this disease. Among the possible targets to fight dengue fever is the viral NS3 protease (NS3(P...

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Detalles Bibliográficos
Autores principales:	de Almeida, Hugo, Bastos, Izabela M. D., Ribeiro, Bergmann M., Maigret, Bernard, Santana, Jaime M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749139/ https://www.ncbi.nlm.nih.gov/pubmed/23991109 http://dx.doi.org/10.1371/journal.pone.0072402

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