Impaired Tethering and Fusion of GLUT4 Vesicles in Insulin-Resistant Human Adipose Cells

Systemic glucose homeostasis is profoundly influenced by adipose cell function. Here we investigated GLUT4 dynamics in living adipose cells from human subjects with varying BMI and insulin sensitivity index (S(i)) values. Cells were transfected with hemagglutinin (HA)-GLUT4-green fluorescent protein...

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Detalles Bibliográficos
Autores principales: Lizunov, Vladimir A., Lee, Jo-Ping, Skarulis, Monica C., Zimmerberg, Joshua, Cushman, Samuel W., Stenkula, Karin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749349/
https://www.ncbi.nlm.nih.gov/pubmed/23801575
http://dx.doi.org/10.2337/db12-1741

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749349/
https://www.ncbi.nlm.nih.gov/pubmed/23801575
http://dx.doi.org/10.2337/db12-1741

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