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Characterisations of human prostate stem cells reveal deficiency in class I UGT enzymes as a novel mechanism for castration-resistant prostate cancer

BACKGROUND: Evidence increasingly supports that prostate cancer is initiated by the malignant transformation of stem cells (SCs). Furthermore, many SC-signalling pathways are shown to be shared in prostate cancer. Therefore, we planned transcriptome characterisation of adult prostate SCs as a strate...

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Detalles Bibliográficos
Autores principales:	Williamson, S C, Mitter, R, Hepburn, A C, Wilson, L, Mantilla, A, Leung, H Y, Robson, C N, Heer, R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749571/ https://www.ncbi.nlm.nih.gov/pubmed/23880823 http://dx.doi.org/10.1038/bjc.2013.399

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