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Notch-induced transcription factors are predictive of survival and 5-fluorouracil response in colorectal cancer patients

BACKGROUND: The purpose of this study was to evaluate the expression of Notch-induced transcription factors (NTFs) HEY1, HES1 and SOX9 in colorectal cancer (CRC) patients to determine their clinicopathologic and prognostic significance. METHODS: Levels of HEY1, HES1 and SOX9 protein were measured by...

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Detalles Bibliográficos
Autores principales: Candy, P A, Phillips, M R, Redfern, A D, Colley, S M, Davidson, J A, Stuart, L M, Wood, B A, Zeps, N, Leedman, P J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749585/
https://www.ncbi.nlm.nih.gov/pubmed/23900217
http://dx.doi.org/10.1038/bjc.2013.431