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A phase II study of gemcitabine and cisplatin plus sorafenib in patients with advanced biliary adenocarcinomas

BACKGROUND: This study evaluated the addition of sorafenib to gemcitabine and cisplatin in biliary adenocarcinoma first-line therapy. METHODS: Patients with advanced biliary adenocarcinomas received gemcitabine 1000 mg m(−2) and cisplatin 25 mg m(−2) on a 2 weeks on/1 week off cycle and sorafenib 40...

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Detalles Bibliográficos
Autores principales: Lee, J K, Capanu, M, O'Reilly, E M, Ma, J, Chou, J F, Shia, J, Katz, S S, Gansukh, B, Reidy-Lagunes, D, Segal, N H, Yu, K H, Chung, K-Y, Saltz, L B, Abou-Alfa, G K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749586/
https://www.ncbi.nlm.nih.gov/pubmed/23900219
http://dx.doi.org/10.1038/bjc.2013.432