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Increased Occurrence of Valproic Acid-Induced Hyperammonemia in Carriers of T1405N Polymorphism in Carbamoyl Phosphate Synthetase 1 Gene

Numerous cases of severe and life-threatening hyperammonemia (HA) related to the treatment of epileptic seizures with valproic acid (VPA) have been previously reported in the medical literature. The aim of this prospective, multicenter study was to verify the putative association between T1405 polym...

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Detalles Bibliográficos
Autores principales: Janicki, Piotr K., Bezinover, Dmitri, Postula, Marek, Thompson, Robert S., Acharya, Jayant, Acharya, Vinita, McNew, Cathy, Bowman, J. Daniel, Kurkowska-Jastrzebska, Iwona, Mirowska-Guzel, Dagmara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749598/
https://www.ncbi.nlm.nih.gov/pubmed/23997965
http://dx.doi.org/10.1155/2013/261497

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