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Increased Occurrence of Valproic Acid-Induced Hyperammonemia in Carriers of T1405N Polymorphism in Carbamoyl Phosphate Synthetase 1 Gene
Numerous cases of severe and life-threatening hyperammonemia (HA) related to the treatment of epileptic seizures with valproic acid (VPA) have been previously reported in the medical literature. The aim of this prospective, multicenter study was to verify the putative association between T1405 polym...
Autores principales: | Janicki, Piotr K., Bezinover, Dmitri, Postula, Marek, Thompson, Robert S., Acharya, Jayant, Acharya, Vinita, McNew, Cathy, Bowman, J. Daniel, Kurkowska-Jastrzebska, Iwona, Mirowska-Guzel, Dagmara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749598/ https://www.ncbi.nlm.nih.gov/pubmed/23997965 http://dx.doi.org/10.1155/2013/261497 |
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