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Minocycline alleviates beta-amyloid protein and tau pathology via restraining neuroinflammation induced by diabetic metabolic disorder

BACKGROUND: Compelling evidence has shown that diabetic metabolic disorder plays a critical role in the pathogenesis of Alzheimer’s disease, including increased expression of β-amyloid protein (Aβ) and tau protein. Evidence has supported that minocycline, a tetracycline derivative, protects against...

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Detalles Bibliográficos
Autores principales: Cai, Zhiyou, Yan, Yong, Wang, Yonglong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749817/
https://www.ncbi.nlm.nih.gov/pubmed/23983461
http://dx.doi.org/10.2147/CIA.S46536