Cargando…

Minocycline alleviates beta-amyloid protein and tau pathology via restraining neuroinflammation induced by diabetic metabolic disorder

BACKGROUND: Compelling evidence has shown that diabetic metabolic disorder plays a critical role in the pathogenesis of Alzheimer’s disease, including increased expression of β-amyloid protein (Aβ) and tau protein. Evidence has supported that minocycline, a tetracycline derivative, protects against...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cai, Zhiyou, Yan, Yong, Wang, Yonglong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2013
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749817/ https://www.ncbi.nlm.nih.gov/pubmed/23983461 http://dx.doi.org/10.2147/CIA.S46536

Ejemplares similares

Ameliorating Alzheimer’s-like Pathology by Minocycline via Inhibiting Cdk5/p25 Signaling
por: Zhao, Yu, et al.
Publicado: (2022)

Intravenous Injection of PHF-Tau Proteins From Alzheimer Brain Exacerbates Neuroinflammation, Amyloid Beta, and Tau Pathologies in 5XFAD Transgenic Mice
por: Houben, Sarah, et al.
Publicado: (2020)

The Contribution of Tau, Amyloid-Beta and Alpha-Synuclein Pathology to Dementia in Lewy Body Disorders
por: Irwin, David J., et al.
Publicado: (2018)

Mitochondrial Calcium Deregulation in the Mechanism of Beta-Amyloid and Tau Pathology
por: Esteras, Noemi, et al.
Publicado: (2020)

The Amyloid-Tau-Neuroinflammation Axis in the Context of Cerebral Amyloid Angiopathy
por: Cisternas, Pablo, et al.
Publicado: (2019)

Altered filamin A enables amyloid beta-induced tau hyperphosphorylation and neuroinflammation in Alzheimer’s disease
por: Burns, Lindsay H., et al.
Publicado: (2017)

Minocycline corrects early, pre-plaque neuroinflammation and inhibits BACE-1 in a transgenic model of Alzheimer's disease-like amyloid pathology
por: Ferretti, Maria Teresa, et al.
Publicado: (2012)

The relationships between neuroinflammation, beta-amyloid and tau deposition in Alzheimer’s disease: a longitudinal PET study
por: Ismail, Rola, et al.
Publicado: (2020)

Impaired autophagy in amyloid-beta pathology: A traditional review of recent Alzheimer's research
por: Yuan, Minghao, et al.
Publicado: (2023)

Transmission of amyloid-beta and tau pathologies is associated with cognitive impairments in a primate
por: Lam, Suzanne, et al.
Publicado: (2021)

Synergistic interaction of high blood pressure and cerebral beta-amyloid on tau pathology
por: Kim, Taewon, et al.
Publicado: (2022)

Autophagy dysfunction upregulates beta-amyloid peptides via enhancing the activity of γ-secretase complex
por: Cai, Zhiyou, et al.
Publicado: (2015)

FLZ Alleviates the Memory Deficits in Transgenic Mouse Model of Alzheimer’s Disease via Decreasing Beta-Amyloid Production and Tau Hyperphosphorylation
por: Bao, Xiu-Qi, et al.
Publicado: (2013)

Soluble P‐tau217 reflects amyloid and tau pathology and mediates the association of amyloid with tau
por: Mattsson‐Carlgren, Niklas, et al.
Publicado: (2021)

Insulin Resistance as a Link between Amyloid-Beta and Tau Pathologies in Alzheimer’s Disease
por: Mullins, Roger J., et al.
Publicado: (2017)

Federated Morphometry Feature Selection for Hippocampal Morphometry Associated Beta-Amyloid and Tau Pathology
por: Wu, Jianfeng, et al.
Publicado: (2021)

What Are the Molecular Mechanisms by Which Functional Bacterial Amyloids Influence Amyloid Beta Deposition and Neuroinflammation in Neurodegenerative Disorders?
por: Friedland, Robert P., et al.
Publicado: (2020)

Immature Persimmon Suppresses Amyloid Beta (Aβ) Mediated Cognitive Dysfunction via Tau Pathology in ICR Mice
por: Yoo, Seul-Ki, et al.
Publicado: (2021)

Plasma amyloid beta levels are associated with cerebral amyloid and tau deposition
por: Risacher, Shannon L., et al.
Publicado: (2019)

Brainstem Quadruple Aberrant Hyperphosphorylated Tau, Beta-Amyloid, Alpha-Synuclein and TDP-43 Pathology, Stress and Sleep Behavior Disorders
por: Calderón-Garcidueñas, Lilian, et al.
Publicado: (2021)

Melatonin Alleviates Neuroinflammation and Metabolic Disorder in DSS-Induced Depression Rats
por: Lv, Wei-jie, et al.
Publicado: (2020)

Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia
por: Henry, Christopher J, et al.
Publicado: (2008)

Amyloid-beta and tau pathologies act synergistically to induce novel disease stage-specific microglia subtypes
por: Kim, Dong Won, et al.
Publicado: (2022)

Neuroinflammation in Lyme neuroborreliosis affects amyloid metabolism
por: Mattsson, Niklas, et al.
Publicado: (2010)

HDL-bound sphingosine 1-phosphate restrains lymphopoiesis and neuroinflammation
por: Blaho, Victoria A., et al.
Publicado: (2015)

Applications of amyloid, tau, and neuroinflammation PET imaging to Alzheimer's disease and mild cognitive impairment
por: Chandra, Avinash, et al.
Publicado: (2019)

Detection of Alzheimer's disease amyloid beta 1‐42, p‐tau, and t‐tau assays
por: van Harten, Argonde C., et al.
Publicado: (2021)

Degradation of insulin amyloid by antibiotic minocycline and formation of toxic intermediates
por: Mori, Wakako, et al.
Publicado: (2021)

Obesity impacts brain metabolism and structure independently of amyloid and tau pathology in healthy elderly
por: Pegueroles, Jordi, et al.
Publicado: (2020)

Small molecule modulation of the p75 neurotrophin receptor inhibits multiple amyloid beta-induced tau pathologies
por: Yang, Tao, et al.
Publicado: (2020)

Phenylindanes in Brewed Coffee Inhibit Amyloid-Beta and Tau Aggregation
por: Mancini, Ross S., et al.
Publicado: (2018)

The Role of Amyloid-Beta and Tau in the Early Pathogenesis of Alzheimer’s Disease
por: Yin, Xiaomin, et al.
Publicado: (2021)

Amyloid-beta peptide and tau protein crosstalk in Alzheimer’s disease
por: Roda, Alejandro R., et al.
Publicado: (2022)

Preclinical amyloid pathology biomarker positivity: effects on tau pathology and neurodegeneration
por: Höglund, K, et al.
Publicado: (2017)

Convergence of Amyloid-β and Tau Pathologies on Mitochondria In Vivo
por: Eckert, Anne, et al.
Publicado: (2010)

The Dichotomy of Alzheimer’s Disease Pathology: Amyloid-β and Tau
por: Ashford, J. Wesson
Publicado: (2019)

Prediction of Cerebral Amyloid Pathology Based on Plasma Amyloid and Tau Related Markers
por: Chen, Ting-Bin, et al.
Publicado: (2021)

Plasma pyroglutamate‐modified amyloid beta differentiates amyloid pathology
por: Wang, Pei‐Ning, et al.
Publicado: (2020)

Would Repurposing Minocycline Alleviate Neurologic Manifestations of COVID-19?
por: Oliveira, Aline C., et al.
Publicado: (2020)

Hepatic and cardiac implications of increased toxic amyloid-beta serum level in lipopolysaccharide-induced neuroinflammation in rats: new insights into alleviating therapeutic interventions
por: Anwar, Mai M., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_bvbmsgts02jia95ibhpdmv5p13