Histone Variant HTZ1 Shows Extensive Epistasis with, but Does Not Increase Robustness to, New Mutations

Biological systems produce phenotypes that appear to be robust to perturbation by mutations and environmental variation. Prior studies identified genes that, when impaired, reveal previously cryptic genetic variation. This result is typically interpreted as evidence that the disrupted gene normally...

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Detalles Bibliográficos
Autores principales: Richardson, Joshua B., Uppendahl, Locke D., Traficante, Maria K., Levy, Sasha F., Siegal, Mark L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749942/
https://www.ncbi.nlm.nih.gov/pubmed/23990806
http://dx.doi.org/10.1371/journal.pgen.1003733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749942/
https://www.ncbi.nlm.nih.gov/pubmed/23990806
http://dx.doi.org/10.1371/journal.pgen.1003733

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