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Transcriptional Regulation of Lineage Commitment - A Stochastic Model of Cell Fate Decisions
Molecular mechanisms employed by individual multipotent cells at the point of lineage commitment remain largely uncharacterized. Current paradigms span from instructive to noise-driven mechanisms. Of considerable interest is also whether commitment involves a limited set of genes or the entire trans...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749951/ https://www.ncbi.nlm.nih.gov/pubmed/23990771 http://dx.doi.org/10.1371/journal.pcbi.1003197 |