Aspergillus Galactosaminogalactan Mediates Adherence to Host Constituents and Conceals Hyphal β-Glucan from the Immune System

Aspergillus fumigatus is the most common cause of invasive mold disease in humans. The mechanisms underlying the adherence of this mold to host cells and macromolecules have remained elusive. Using mutants with different adhesive properties and comparative transcriptomics, we discovered that the gen...

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Detalles Bibliográficos
Autores principales: Gravelat, Fabrice N., Beauvais, Anne, Liu, Hong, Lee, Mark J., Snarr, Brendan D., Chen, Dan, Xu, Wenjie, Kravtsov, Ilia, Hoareau, Christopher M. Q., Vanier, Ghyslaine, Urb, Mirjam, Campoli, Paolo, Al Abdallah, Qusai, Lehoux, Melanie, Chabot, Josée C., Ouimet, Marie-Claude, Baptista, Stefanie D., Fritz, Jörg H., Nierman, William C., Latgé, Jean Paul, Mitchell, Aaron P., Filler, Scott G., Fontaine, Thierry, Sheppard, Donald C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749958/
https://www.ncbi.nlm.nih.gov/pubmed/23990787
http://dx.doi.org/10.1371/journal.ppat.1003575

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