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Phosphorylation of Calcineurin at a Novel Serine-Proline Rich Region Orchestrates Hyphal Growth and Virulence in Aspergillus fumigatus

The fungus Aspergillus fumigatus is a leading infectious killer in immunocompromised patients. Calcineurin, a calmodulin (CaM)-dependent protein phosphatase comprised of calcineurin A (CnaA) and calcineurin B (CnaB) subunits, localizes at the hyphal tips and septa to direct A. fumigatus invasion and...

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Detalles Bibliográficos
Autores principales: Juvvadi, Praveen R., Gehrke, Christopher, Fortwendel, Jarrod R., Lamoth, Frédéric, Soderblom, Erik J., Cook, Erik C., Hast, Michael A., Asfaw, Yohannes G., Moseley, M. Arthur, Creamer, Trevor P., Steinbach, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749960/
https://www.ncbi.nlm.nih.gov/pubmed/23990785
http://dx.doi.org/10.1371/journal.ppat.1003564