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Phosphorylation of Calcineurin at a Novel Serine-Proline Rich Region Orchestrates Hyphal Growth and Virulence in Aspergillus fumigatus
The fungus Aspergillus fumigatus is a leading infectious killer in immunocompromised patients. Calcineurin, a calmodulin (CaM)-dependent protein phosphatase comprised of calcineurin A (CnaA) and calcineurin B (CnaB) subunits, localizes at the hyphal tips and septa to direct A. fumigatus invasion and...
Autores principales: | Juvvadi, Praveen R., Gehrke, Christopher, Fortwendel, Jarrod R., Lamoth, Frédéric, Soderblom, Erik J., Cook, Erik C., Hast, Michael A., Asfaw, Yohannes G., Moseley, M. Arthur, Creamer, Trevor P., Steinbach, William J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749960/ https://www.ncbi.nlm.nih.gov/pubmed/23990785 http://dx.doi.org/10.1371/journal.ppat.1003564 |
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