Replication Vesicles are Load- and Choke-Points in the Hepatitis C Virus Lifecycle

Hepatitis C virus (HCV) infection develops into chronicity in 80% of all patients, characterized by persistent low-level replication. To understand how the virus establishes its tightly controlled intracellular RNA replication cycle, we developed the first detailed mathematical model of the initial...

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Detalles Bibliográficos
Autores principales: Binder, Marco, Sulaimanov, Nurgazy, Clausznitzer, Diana, Schulze, Manuel, Hüber, Christian M., Lenz, Simon M., Schlöder, Johannes P., Trippler, Martin, Bartenschlager, Ralf, Lohmann, Volker, Kaderali, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749965/
https://www.ncbi.nlm.nih.gov/pubmed/23990783
http://dx.doi.org/10.1371/journal.ppat.1003561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749965/
https://www.ncbi.nlm.nih.gov/pubmed/23990783
http://dx.doi.org/10.1371/journal.ppat.1003561

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