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Replication Vesicles are Load- and Choke-Points in the Hepatitis C Virus Lifecycle
Hepatitis C virus (HCV) infection develops into chronicity in 80% of all patients, characterized by persistent low-level replication. To understand how the virus establishes its tightly controlled intracellular RNA replication cycle, we developed the first detailed mathematical model of the initial...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749965/ https://www.ncbi.nlm.nih.gov/pubmed/23990783 http://dx.doi.org/10.1371/journal.ppat.1003561 |