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Stimulation of α(1a) Adrenergic Receptors Induces Cellular Proliferation or Antiproliferative Hypertrophy Dependent Solely on Agonist Concentration
Stimulation of α(1a)Adrenergic Receptors (ARs) is known to have anti-proliferative and hypertrophic effects; however, some studies also suggests this receptor can increase cell proliferation. Surprisingly, we find the α(1a)AR expressed in rat-1 fibroblasts can produce either phenotype, depending exc...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749976/ https://www.ncbi.nlm.nih.gov/pubmed/23991110 http://dx.doi.org/10.1371/journal.pone.0072430 |