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In Vivo Imaging of Trypanosome-Brain Interactions and Development of a Rapid Screening Test for Drugs against CNS Stage Trypanosomiasis
Human African trypanosomiasis (HAT) manifests in two stages of disease: firstly, haemolymphatic, and secondly, an encephalitic phase involving the central nervous system (CNS). New drugs to treat the second-stage disease are urgently needed, yet testing of novel drug candidates is a slow process bec...
Autores principales: | Myburgh, Elmarie, Coles, Jonathan A., Ritchie, Ryan, Kennedy, Peter G. E., McLatchie, Alex P., Rodgers, Jean, Taylor, Martin C., Barrett, Michael P., Brewer, James M., Mottram, Jeremy C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749981/ https://www.ncbi.nlm.nih.gov/pubmed/23991236 http://dx.doi.org/10.1371/journal.pntd.0002384 |
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