Rapid and Tunable Control of Protein Stability in Caenorhabditis elegans Using a Small Molecule

Destabilizing domains are conditionally unstable protein domains that can be fused to a protein of interest resulting in degradation of the fusion protein in the absence of stabilizing ligand. These engineered protein domains enable rapid, reversible and dose-dependent control of protein expression...

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Detalles Bibliográficos
Autores principales: Cho, Ukrae, Zimmerman, Stephanie M., Chen, Ling-chun, Owen, Elliot, Kim, Jesse V., Kim, Stuart K., Wandless, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750007/
https://www.ncbi.nlm.nih.gov/pubmed/23991108
http://dx.doi.org/10.1371/journal.pone.0072393

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