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Inverse Regulation of EGFR/HER1 and HER2-4 in Normal and Malignant Human Breast Tissue
Cross-talk between the estrogen and the EGFR/HER signalling pathways has been suggested as a potential cause of resistance to endocrine therapy in breast cancer. Here, we determined HER1-4 receptor and neuregulin-1 (NRG1) ligand mRNA expression levels in breast cancers and corresponding normal breas...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750010/ https://www.ncbi.nlm.nih.gov/pubmed/23991224 http://dx.doi.org/10.1371/journal.pone.0074618 |