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Evidence for Sigma Factor Competition in the Regulation of Alginate Production by Pseudomonas aeruginosa
Alginate overproduction, or mucoidy, plays an important role in the pathogenesis of P. aeruginosa lung infection in cystic fibrosis (CF). Mucoid strains with mucA mutations predominantly populate in chronically-infected patients. However, the mucoid strains can revert to nonmucoidy in vitro through...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750012/ https://www.ncbi.nlm.nih.gov/pubmed/23991093 http://dx.doi.org/10.1371/journal.pone.0072329 |