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Impact of Glutathione Peroxidase-1 Deficiency on Macrophage Foam Cell Formation and Proliferation: Implications for Atherogenesis

Clinical and experimental evidence suggests a protective role for the antioxidant enzyme glutathione peroxidase-1 (GPx-1) in the atherogenic process. GPx-1 deficiency accelerates atherosclerosis and increases lesion cellularity in ApoE(−/−) mice. However, the distribution of GPx-1 within the atheros...

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Detalles Bibliográficos
Autores principales:	Cheng, Fei, Torzewski, Michael, Degreif, Adriana, Rossmann, Heidi, Canisius, Antje, Lackner, Karl J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750037/ https://www.ncbi.nlm.nih.gov/pubmed/23991041 http://dx.doi.org/10.1371/journal.pone.0072063

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