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Hepatitis C Virus NS5A Inhibits Mixed Lineage Kinase 3 to Block Apoptosis
Hepatitis C virus (HCV) infection results in the activation of numerous stress responses including oxidative stress, with the potential to induce an apoptotic state. Previously we have shown that HCV attenuates the stress-induced, p38MAPK-mediated up-regulation of the K(+) channel Kv2.1, to maintain...
Autores principales: | Amako, Yutaka, Igloi, Zsofia, Mankouri, Jamel, Kazlauskas, Arunas, Saksela, Kalle, Dallas, Mark, Peers, Chris, Harris, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750171/ https://www.ncbi.nlm.nih.gov/pubmed/23857585 http://dx.doi.org/10.1074/jbc.M113.491985 |
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