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Hepatitis C Virus NS5A Inhibits Mixed Lineage Kinase 3 to Block Apoptosis

Hepatitis C virus (HCV) infection results in the activation of numerous stress responses including oxidative stress, with the potential to induce an apoptotic state. Previously we have shown that HCV attenuates the stress-induced, p38MAPK-mediated up-regulation of the K(+) channel Kv2.1, to maintain...

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Detalles Bibliográficos
Autores principales: Amako, Yutaka, Igloi, Zsofia, Mankouri, Jamel, Kazlauskas, Arunas, Saksela, Kalle, Dallas, Mark, Peers, Chris, Harris, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750171/
https://www.ncbi.nlm.nih.gov/pubmed/23857585
http://dx.doi.org/10.1074/jbc.M113.491985

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