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ERK-associated changes in E2F4 phosphorylation, localization and transcriptional activity during mitogenic stimulation in human intestinal epithelial crypt cells
BACKGROUND: The transcription factor E2F4 controls proliferation of normal and cancerous intestinal epithelial cells. E2F4 localization in normal human intestinal epithelial cells (HIEC) is cell cycle-dependent, being cytoplasmic in quiescent differentiated cells but nuclear in proliferative cells....
Autores principales: | Paquin, Marie-Christine, Cagnol, Sébastien, Carrier, Julie C, Leblanc, Caroline, Rivard, Nathalie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750237/ https://www.ncbi.nlm.nih.gov/pubmed/23919615 http://dx.doi.org/10.1186/1471-2121-14-33 |
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