Microarray profiling reveals suppressed interferon stimulated gene program in fibroblasts from scleroderma-associated interstitial lung disease

BACKGROUND: Interstitial lung disease is a major cause of morbidity and mortality in systemic sclerosis (SSc), with insufficiently effective treatment options. Progression of pulmonary fibrosis involves expanding populations of fibroblasts, and the accumulation of extracellular matrix proteins. Char...

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Detalles Bibliográficos
Autores principales: Lindahl, Gisela E, Stock, Carmel JW, Shi-Wen, Xu, Leoni, Patricia, Sestini, Piersante, Howat, Sarah L, Bou-Gharios, George, Nicholson, Andrew G, Denton, Christopher P, Grutters, Jan C, Maher, Toby M, Wells, Athol U, Abraham, David J, Renzoni, Elisabetta A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750263/
https://www.ncbi.nlm.nih.gov/pubmed/23915349
http://dx.doi.org/10.1186/1465-9921-14-80

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