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Automethylation of protein arginine methyltransferase 6 (PRMT6) regulates its stability and its anti-HIV-1 activity

BACKGROUND: Protein arginine methyltransferase 6 (PRMT6) is a nuclear enzyme that methylates arginine residues on histones and transcription factors. In addition, PRMT6 inhibits HIV-1 replication in cell culture by directly methylating and interfering with the functions of several HIV-1 proteins, i....

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Detalles Bibliográficos
Autores principales:	Singhroy, Diane N, Mesplède, Thibault, Sabbah, Arielle, Quashie, Peter K, Falgueyret, Jean-Pierre, Wainberg, Mark A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750301/ https://www.ncbi.nlm.nih.gov/pubmed/23866860 http://dx.doi.org/10.1186/1742-4690-10-73

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