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Synonymous site conservation in the HIV-1 genome

BACKGROUND: Synonymous or silent mutations are usually thought to evolve neutrally. However, accumulating recent evidence has demonstrated that silent mutations may destabilize RNA structures or disrupt cis regulatory motifs superimposed on coding sequences. Such observations suggest the existence o...

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Detalles Bibliográficos
Autores principales:	Mayrose, Itay, Stern, Adi, Burdelova, Ela O, Sabo, Yosef, Laham-Karam, Nihay, Zamostiano, Rachel, Bacharach, Eran, Pupko, Tal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750384/ https://www.ncbi.nlm.nih.gov/pubmed/23914950 http://dx.doi.org/10.1186/1471-2148-13-164

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