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Estimating DNA polymorphism from next generation sequencing data with high error rate by dual sequencing applications

BACKGROUND: As the error rate is high and the distribution of errors across sites is non-uniform in next generation sequencing (NGS) data, it has been a challenge to estimate DNA polymorphism (θ) accurately from NGS data. RESULTS: By computer simulations, we compare the two methods of data acquisiti...

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Detalles Bibliográficos
Autores principales:	He, Ziwen, Li, Xinnian, Ling, Shaoping, Fu, Yun-Xin, Hungate, Eric, Shi, Suhua, Wu, Chung-I
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750404/ https://www.ncbi.nlm.nih.gov/pubmed/23919637 http://dx.doi.org/10.1186/1471-2164-14-535

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