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Specific mutations in H5N1 mainly impact the magnitude and velocity of the host response in mice

BACKGROUND: Influenza infection causes respiratory disease that can lead to death. The complex interplay between virus-encoded and host-specific pathogenicity regulators – and the relative contributions of each toward viral pathogenicity – is not well-understood. RESULTS: By analyzing a collection o...

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Detalles Bibliográficos
Autores principales:	Tchitchek, Nicolas, Eisfeld, Amie J, Tisoncik-Go, Jennifer, Josset, Laurence, Gralinski, Lisa E, Bécavin, Christophe, Tilton, Susan C, Webb-Robertson, Bobbie-Jo, Ferris, Martin T, Totura, Allison L, Li, Chengjun, Neumann, Gabriele, Metz, Thomas O, Smith, Richard D, Waters, Katrina M, Baric, Ralph, Kawaoka, Yoshihiro, Katze, Michael G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750405/ https://www.ncbi.nlm.nih.gov/pubmed/23895213 http://dx.doi.org/10.1186/1752-0509-7-69

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