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Incidence rate of symptomatic venous thromboembolic disease in patients from a medical care program in Buenos Aires, Argentina: a prospective cohort

BACKGROUND: The incidence of venous thromboembolic disease (VTED) is estimated to be, on average, 1–2 cases per 1,000 individuals per year worldwide. There are few data concerning the incidence rate (IR) of VTED in the Argentinean population at large. Our aim was to estimate the IR of VTED at the It...

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Autores principales: Vázquez, Fernando Javier, Posadas-Martínez, María Lourdes, Vicens, Jimena, González Bernaldo de Quirós, Fernán, Giunta, Diego Hernán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750410/
https://www.ncbi.nlm.nih.gov/pubmed/24060275
http://dx.doi.org/10.1186/1477-9560-11-16
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author Vázquez, Fernando Javier
Posadas-Martínez, María Lourdes
Vicens, Jimena
González Bernaldo de Quirós, Fernán
Giunta, Diego Hernán
author_facet Vázquez, Fernando Javier
Posadas-Martínez, María Lourdes
Vicens, Jimena
González Bernaldo de Quirós, Fernán
Giunta, Diego Hernán
author_sort Vázquez, Fernando Javier
collection PubMed
description BACKGROUND: The incidence of venous thromboembolic disease (VTED) is estimated to be, on average, 1–2 cases per 1,000 individuals per year worldwide. There are few data concerning the incidence rate (IR) of VTED in the Argentinean population at large. Our aim was to estimate the IR of VTED at the Italian Hospital Medical Care Program (IHMCP) in Buenos Aires, the most populous city in Argentina. METHODS: This prospective cohort study evaluated all consecutive incident cases of pulmonary thromboembolism (PTE) and deep vein thrombosis (DVT) confirmed in patients over the age of 17 who were members of the IHMCP from June 2006 to May 2012. Any patient who had an initial confirmed VTED episode and was a member of the IHMCP at the time of diagnosis was considered an incident case. RESULTS: There were 1,138 cases of VTED for 687,871 person-years of follow-up. The crude IR of VTED was 1.65 (95% CI: 1.56 to 1.75) per 1,000 person-years. The highest IR was found in subjects >80 years old (5.92 per 1,000 person years; 95% CI: 5.41 to 6.49). The IRs adjusted to the population of the city of Buenos Aires were 0.90 (95% CI: 0.84 to 0.95) for VTED, 0.71 (95% CI: 0.66 to 0.76) for DVT, and 0.34 (95% CI: 0.31 to 0.37) for PTE. CONCLUSIONS: VTED is a common health problem with a high IR in members of the IHMCP, especially the elderly. This is the first paper to report prospectively the cumulative incidence of VTED in Latin America.
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spelling pubmed-37504102013-08-24 Incidence rate of symptomatic venous thromboembolic disease in patients from a medical care program in Buenos Aires, Argentina: a prospective cohort Vázquez, Fernando Javier Posadas-Martínez, María Lourdes Vicens, Jimena González Bernaldo de Quirós, Fernán Giunta, Diego Hernán Thromb J Original Clinical Investigation BACKGROUND: The incidence of venous thromboembolic disease (VTED) is estimated to be, on average, 1–2 cases per 1,000 individuals per year worldwide. There are few data concerning the incidence rate (IR) of VTED in the Argentinean population at large. Our aim was to estimate the IR of VTED at the Italian Hospital Medical Care Program (IHMCP) in Buenos Aires, the most populous city in Argentina. METHODS: This prospective cohort study evaluated all consecutive incident cases of pulmonary thromboembolism (PTE) and deep vein thrombosis (DVT) confirmed in patients over the age of 17 who were members of the IHMCP from June 2006 to May 2012. Any patient who had an initial confirmed VTED episode and was a member of the IHMCP at the time of diagnosis was considered an incident case. RESULTS: There were 1,138 cases of VTED for 687,871 person-years of follow-up. The crude IR of VTED was 1.65 (95% CI: 1.56 to 1.75) per 1,000 person-years. The highest IR was found in subjects >80 years old (5.92 per 1,000 person years; 95% CI: 5.41 to 6.49). The IRs adjusted to the population of the city of Buenos Aires were 0.90 (95% CI: 0.84 to 0.95) for VTED, 0.71 (95% CI: 0.66 to 0.76) for DVT, and 0.34 (95% CI: 0.31 to 0.37) for PTE. CONCLUSIONS: VTED is a common health problem with a high IR in members of the IHMCP, especially the elderly. This is the first paper to report prospectively the cumulative incidence of VTED in Latin America. BioMed Central 2013-08-01 /pmc/articles/PMC3750410/ /pubmed/24060275 http://dx.doi.org/10.1186/1477-9560-11-16 Text en Copyright © 2013 Vázquez et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Clinical Investigation
Vázquez, Fernando Javier
Posadas-Martínez, María Lourdes
Vicens, Jimena
González Bernaldo de Quirós, Fernán
Giunta, Diego Hernán
Incidence rate of symptomatic venous thromboembolic disease in patients from a medical care program in Buenos Aires, Argentina: a prospective cohort
title Incidence rate of symptomatic venous thromboembolic disease in patients from a medical care program in Buenos Aires, Argentina: a prospective cohort
title_full Incidence rate of symptomatic venous thromboembolic disease in patients from a medical care program in Buenos Aires, Argentina: a prospective cohort
title_fullStr Incidence rate of symptomatic venous thromboembolic disease in patients from a medical care program in Buenos Aires, Argentina: a prospective cohort
title_full_unstemmed Incidence rate of symptomatic venous thromboembolic disease in patients from a medical care program in Buenos Aires, Argentina: a prospective cohort
title_short Incidence rate of symptomatic venous thromboembolic disease in patients from a medical care program in Buenos Aires, Argentina: a prospective cohort
title_sort incidence rate of symptomatic venous thromboembolic disease in patients from a medical care program in buenos aires, argentina: a prospective cohort
topic Original Clinical Investigation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750410/
https://www.ncbi.nlm.nih.gov/pubmed/24060275
http://dx.doi.org/10.1186/1477-9560-11-16
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