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Evaluating a linear k-mer model for protein-DNA interactions using high-throughput SELEX data

Transcription factor (TF) binding to DNA can be modeled in a number of different ways. It is highly debated which modeling methods are the best, how the models should be built and what can they be applied to. In this study a linear k-mer model proposed for predicting TF specificity in protein bindin...

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Detalles Bibliográficos
Autores principales: Kähärä, Juhani, Lähdesmäki, Harri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750486/
https://www.ncbi.nlm.nih.gov/pubmed/24267147
http://dx.doi.org/10.1186/1471-2105-14-S10-S2